Postgraduate Details

DIT School of Physics

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Peter Knief Dipl.-Ing. (FH) Brief Biography Previously self employed as an IT consultant and solution provider in Cologne (Germany) between 1994-2005 with a highly developmental oriented patronage. Diploma in biomedical technology at the University of Applied Science at Aachen (Germany) in 2006. Thesis title 'Signal Conditioning in Raman Spectroscopy Signals'. During Diploma joined the RESC & POMM workgroup for studies of the application of vibrational spectroscopy to the non-invasive analysis of function in biological systems, supporting the work of Fiona Lyng, Eoghan Ó Faoláin, Aidan D. Meade, Hugh J. Byrne. MPhil candidate since November 2006 working in the field of Spectroscopy of Single Wall Carbon Nano Tubes in interaction with biological materials. Member of the Raman Working Group of DASIM, an EU-funded research collaboration involving around 70 scientists and clinicians from 9 European countries. Transfer to PhD register in November 2008 and continuing the work in the field of characterization of biological interactions with Single Wall Carbon Nano Tubes. Research Interests The application of vibrational spectroscopy, Raman spectroscopy in particular, to analyze the interaction of nanomaterials with biological systems in order to access cellular changes (e.g. toxicity) .Long term - to develop Raman spectroscopy as a potential diagnostic high throughput method with special interest in multivariate analysis of spectroscopic data and data precision.  Recent Presentations § Sept. 07, Oral presentation to 12th ECSBM, Paris, European Conference on the Spectroscopy of Biological Molecules § Sept. 07, Poster presentation to Photonics Ireland, Galway § Oct. 07, Poster Presentation at the Joint Conference Nanotechnology, Dublin, Ireland § Oct.07, Poster Presentation at the FTIR Worksop RKI Berlin, Germany § Nov.07, Poster Presentation at ESF-EMBO Symposium on Probing Interactions between Nanoparticles/Biomaterials and Biological Systems, San Feliu de Grixoles, Spain § June 08, Poster Presentation at DASIM Workgroup Meeting, Dublin, Ireland § June 08, International Summer School on Synchrotron Infrared Micro-spectroscopy, Karlsruhe, Germany § Aug. 08, Poster Presentation at ICPS Krakow, Poland § Sept.08, Poster Presentation at BIGSS Summer School, Burren, Ireland § Oct.08, Poster Presentation at SPEC 2008, Sao Jose Dos Campos, Brazil § March 09, Poster Presentation at RCSI NBIP Conference, Dublin Publications Knief, P., et al., "Raman spectroscopy - a potential platform for the rapid measurement of carbon nanotube-induced cytotoxicity", Analyst, 2009, in press Lyng, F. M., et al., "Vibrational spectroscopy for cervical cancer pathology, from biochemical analysis to diagnostic tool." Exp Mol Pathol., 2007. 82(2): p. 121-9. Meade, A.D., et al., "Growth substrate induced functional changes elucidated by FTIR and Raman spectroscopy in in-vitro cultured human keratinocytes" Analytical and Bioanalytical Chemistry, 2006.

contact: § peter(at)knief.de § t: +353 1 402 7929 § f: +353 1 402 7901

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